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1.
J Diet Suppl ; 21(3): 374-388, 2024.
Article En | MEDLINE | ID: mdl-38180010

Osteoarthritis (OA) is an age-related degenerative joint disease with a great impact on patients' well-being and quality of life. This is an observational, open, single-arm multicenter study aimed to evaluate the effectiveness of a nutritional supplement in patients with knee and/or hip OA. A total of 186 patients were recruited from Spanish centers and received a supplement containing hydrolyzed collagen (3000 mg), chondroitin sulfate (800 mg), glucosamine sulfate (700 mg), turmeric extract (250 mg) and devil's claw (150 mg), once daily during 6 months. The primary outcome was the patients' self-perceived pain in the affected joints measured with a visual analogue scale (VAS). Secondary outcome was the patient's functioning, measured with the Lequesne Functional Index and the Western Ontario and McMaster Universities Arthritis Index (WOMAC). Participants showed a significant reduction in self-perceived pain after 3 (mean reduction ± standard deviation, 1.99 ± 1.05) and 6 months (3.57 ± 1.39) of treatment (p < 0.0001 in both comparisons). Lequesne Functional Index score was significantly reduced at 3 months (3.86 ± 2.94) and at 6 months (6.73 ± 4.30) of treatment (p < 0.0001 in both comparisons). The WOMAC index was also significantly reduced after 3 (14.24 ± 10.04) and 6 months (26.43 ± 17.35) of treatment (p < 0.0001 in both comparisons). Significant reductions in WOMAC subdomains (p < 0.0001 in all comparisons) were observed. No severe adverse events were reported during the study. The main results arising from this study show that this nutritional supplementation can improve OA-related symptoms and physical function with a good safety profile in patients with hip and/or knee OA.


Chondroitin Sulfates , Osteoarthritis, Knee , Humans , Chondroitin Sulfates/therapeutic use , Glucosamine/therapeutic use , Quality of Life , Dietary Supplements , Pain/drug therapy , Pain/complications , Osteoarthritis, Knee/drug therapy , Treatment Outcome , Collagen
2.
J Orthop Surg Res ; 17(1): 25, 2022 Jan 15.
Article En | MEDLINE | ID: mdl-35033133

BACKGROUND: This study aimed to assess whether use of continuous passive motion (CPM) could improve range of motion in patients after total knee arthroplasty (TKA), if it could affect the surgical wound aspect (SWA) and if it could influence on pain management after TKA. METHODS: We randomized 210 patients in two groups, 102 patients in the CPM group, who received a standard rehabilitation protocol together with CPM application; and 108 patients in the no-CPM group, without CPM. Variables as knee motion (flexion, extension, range of motion) and pain were measured before surgery, on the 1st, 2nd and 3rd postoperative day, and in the 2nd, 6th, 12th and 24th postoperative weeks following TKA. The SWA was determined by the "surgical wound aspect score" (SWAS) in the next 48 h after surgery. This scale analyzes swelling, erythema, hematoma, blood drainage and blisters. RESULTS: There was an improvement in the knee motion over the course of follow-up in both groups, without significant difference in flexion parameter. We found no significant differences in the total score of SWA, except for hematoma, with less severity in the CPM group. Furthermore, we found no differences in the others SWAS parameters and pain. CONCLUSIONS: The application of CPM does not provide benefit to our patients undergoing TKA in terms of either improved flexion mobility or decreased pain. No relationship was found between the use of CPM and the global score of SWA following a TKA, except for a decrease in hematoma appearance.


Arthroplasty, Replacement, Knee/rehabilitation , Knee Joint/surgery , Motion Therapy, Continuous Passive/methods , Pain Management , Range of Motion, Articular/physiology , Surgical Wound , Aged , Arthroplasty, Replacement, Knee/adverse effects , Female , Humans , Male , Middle Aged , Pain
3.
Rev. multidiscip. gerontol ; 21(1): 22-26, ene.-mar. 2011. tab
Article Es | IBECS | ID: ibc-90684

La fractura de fémur es una de las patologías más prevalentes y que provoca una importante morbimortalidad y discapacidad en los pacientes atendidos en los servicios de rehabilitación hospitalarios. El abordaje de la misma ha de ser interdisciplinario, debiendo existir una estrecha relación entre los servicios de urgencias, geriatría, cirugía ortopédica y traumatología y rehabilitación con el objetivo de realizar intervenciones que permitan obtener resultados más eficaces y eficientes. Los servicios de rehabilitación deben garantizar un tratamiento integral de la fractura de fémur. La prevención de los dos factores que predisponen a la misma como son las caídas y la osteoporosis, con intervenciones basadas fundamentalmente en la promoción de la actividad física y el ejercicio terapeútico. El tratamiento rehabilitador del paciente afecto de fractura de fémur ha de tener como objetivo fundamental el recuperar la capacidad de deambulación previa. Para realizar una correcta planificación se deberán tener en cuenta aspectos relacionados con la situación previa del paciente como las enfermedades concomitantes, el grado de funcionalidad y la situación sociofamiliar. Los programas se iniciarán de forma precoz, en el postoperatorio inmediato, estimulando la carga y deambulación en las fases tempranas con el objeto de minimizar las complicaciones de la inmovilización(AU)


A fractured femur is one of the most prevalent diseases and causes significant morbidity-mortality and disability in patients in hospital rehabilitation services. The same approach must be interdisciplinary and should be a close relationship between the emergency services, geriatrics, orthopedics and rehabilitation with the aim of developing interventions that can produce more effective and efficient results. Rehabilitation services should ensure a comprehensive treatment of hip fracture. The prevention of the two factors that predispose to it as are the falls and osteoporosis, mainly based interventions in promoting physical activity and therapeutic exercise. The rehabilitative treatment of the patient suffering from a fractured femur has a fundamental aim recover to walking. For proper planning should take into account issues related to the previous situation of the patient and concomitant diseases, the degree of functionality and social and family situation. The program is initiated early, in the immediate postoperative period, stimulating the load and walking in the early stages in order to minimize(AU)


Humans , Male , Female , Aged , Aged, 80 and over , Femoral Fractures/rehabilitation , Accidental Falls/prevention & control , Accidental Falls/statistics & numerical data , Risk Factors , Mobility Limitation , Femoral Fractures/epidemiology , Accidental Falls/mortality , Hip Fractures/prevention & control , Gait/physiology , Fractures, Stress/prevention & control , Fractures, Stress/rehabilitation
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